Antigen Intraperitoneal Injection of and the Spleen following the Parathymic Lymph Nodes Antibody-producing Cells in the Number Of
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تهیه و تخلیص آنتی‌بادی منوکلونال علیه آنتی‌ژن لیپوآرابینومان مانوزیله مایکوباکتریوم بویس
Background and Objective: Lipoarabinomannan mannesylated (ManLAm) is one of the lipoglycans which forms a considerable percent of Mycobacterium Bovis BCG’ cellular wall. Considering that generation of monoclonal antibody against ManLAM antigen has many applications, specifically, in order to design the diagnostic kit for rapid diagnosing of tuberculosis, so the main objective of this study wa...
متن کاملA Cyclical Appearance of Antibody-producing Cells after a Single Injection of Serum Protein Antigen
After a single intravenous injection of rabbits with aggregated HuIgG, IgM- and IgG-plaque-forming cells (PFC) in both the spleens and peripheral blood of rabbits peaked 5, 13, and 21 days after injection, while almost no PFC could be detected on days 8 and 16. The available data suggest that the secondary peaks of PFC (days 13 and 21) resulted from stimulation of memory cells by persisting ant...
متن کاملIL-17 and IL-4 Producing CD8+ T Cells in Tumor Draining Lymph Nodes of Breast Cancer Patients: Positive Association with Tumor Progression
Background: CD8+ cytotoxic T lymphocytes have been recently divided based on their cytokine expression profile. Objective: To evaluate the percentages of CD8+ lymphocytes and their effector subsets including Tc1, Tc2 and Tc17 in the tumor draining lymph nodes (TDLNs) of patients with breast cancer. Methods: Single cell suspensions were obtained from TDLNs of 42 patients with breast cancer. Stai...
متن کاملImmunological tolerance to microbial antigens I. Absence of specific antibody-containing cells in lymphoid tissue of mice injected at birth with Shigella soluble antigen.
Friedman, Herman (Albert Einstein Medical Center, Philadelphia, Pa.). Immunological tolerance to microbial antigens. I. Absence of specific antibody-containing cells in lymphoid tissue of mice injected at birth with Shigella soluble antigen. J. Bacteriol. 92:390-397. 1966.-Injection of a relatively large concentration of Shigella soluble antigen (SSA) into newborn mice results in specific immun...
متن کاملAdoptive Transfer of Experimental Autoimmune Uveoretinitis in Rats Immunoparhogenic Mechanisms and Hisrologic Features
In order to learn about the immunopathogenic mechanisms of experimental autoimmune uveoretinitis (EAU), the capacity of lymphocytes to transfer the disease was studied. EAU was transferred to naive syngeneic rats by intraperitoneal injection of spleen or lymph node (LN) cells from S-antigen immunized rats, following their incubation in culture with either S-antigen or concanavalin A (Con A). In...
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تاریخ انتشار 2006